Hoffman is a former graduate of Wolfson College, earning a M.A. in philosophy as a Marshall Scholar (1993). In 2003 he co-founded LinkedIn, the world's largest professional networking service. In 2009 he joined Greylock Partners.
In 2016 Hoffman gifted $1M to support entrepreneurship at SaÃ¯d Business School and across the University of Oxford. Hoffman's gift was a founding donation for The Oxford Foundry, a new initiative driven by Oxford SaÃ¯d in collaboration with other departments, where he also acted as Senior Advisor giving his time and advice to help start and scale new ventures.