Moudhy studied philosophy as an undergraduate and earned a B.A. in Philosophy from Columbia University's Columbia College. She went on to complete an MPhil in Cuneiform Studies and a DPhil in Oriental Studies at the University of Oxford (Wolfson College), where she now researches the use of metaphor in descriptions of mental distress in cuneiform medical texts. She teaches Akkadian text classes and modules in the history of science in Mesopotamia at the Oriental Institute.
Research interests include the history of science, medicine, and technology; science and medicine in the ancient Middle East; Iraq; cuneiform; Akkadian language; ancient North Arabian languages and scripts; archaeology; Assyriology; and historiography of Assyriology.